MURDOCK Proposal Concept Form

Duke's MURDOCK Study welcomes opportunities for collaboration with academia, industry, and other partners.

The MURDOCK Study has collected data and biospecimens from a large cohort of engaged participants, all of which are accessible for analysis, or recruitment into new research studies. The MURDOCK Study team asks that you complete this proposal concept form as a first step, so that we may better understand your interest, and ways in which we can support your research.

We will use the information you provide to evaluate methodology and feasability, and to develop an initial scope and budget for further discussion.

Thank you for your interest in the MURDOCK Study!




Sections designated with an asterisk (*) are required for submission.


Submit Last Name, First Name plus credentials.



















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The MURDOCK Study Biorepository contains biospecimens readily accessible for research opportunities and collaborations.

Available specimen types include plasma, serum, whole blood for DNA (stored in EDTA), whole blood for RNA (stored in PAXgene RNA), buffy coat, and urine. Extracted DNA and RNA may also be available.

Please indicate specimens of interest, as well as volume required for planned analyses.



Specify the volume required for planned analysis in microliters. Please include any overage requirements.


Specify the volume required for planned analysis in microliters. Please include any overage requirements.


Specify the quantity of RNA in micrograms required for planned analysis, or by concentration and volume in micrograms and microliters. Please include any overage requirements.


Specify the quantity of DNA in micrograms required for planned analysis, or by concentration and volume in micrograms and microliters. Please include any overage requirements.


Specify the volume required for planned analysis in microliters or mililters. Please include any overage requirements.


If there are additional requirements for planned analyses, such as preparation methodology, tube type, or shipping conditions, please specify them here.


The MURDOCK Study infrastructure can also support prospective sample collection as part of a study design. If prospectively collected biospecimen samples are required for this proposed study, mark below which sample types will be required.








Please describe any particular recruitment strategy that should be undertaken or considered for identifying potential study volunteers.



The MURDOCK Study Registry and Biorepository provides a wide spectrum of data.

Resources that may be helpful for this section include:

Participant Enrollment Questionnaire and Annual Follow-up Form: http://www.murdock-study.com/ongoing-studies/community-registry-and-biorepository/

MURDOCK Study Data Dictionary: http://murdock-study.com/services/data-dictionary/

Please enumerate data elements or domains of interest from the MURDOCK Study Registry.



Use the following outline to generate the required Methods section of this application.


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Include power calculations, if applicable.




Discuss a plan for how data will be retrieved, captured, and stored.




Please enumerate the proposed study's timeline from start up to closeout including the duration of available funding or anticipated duration, if funded.


Briefly describe plans for dissemination of results (e.g. conferences, manuscripts, opportunities for other partnerships).




Please upload your proposed budget here. Materials included as an Appendix should also be uploaded here as a PDF file (if other attachments are included with this application).


Include what sources of funding will be targeted for this project and applicable submission dates.


Include new data collection instruments and/or other supporting materials should be uploaded under the Budget section.







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