The AFL funding application must include the tentative specific aims of the proposed R01-type grant and should identify gaps in preliminary data that need to be filled before finalizing the submission. If the grant is a resubmission, the relevant reviewer comments can also be provided. In addition to the above, applications must be accompanied by a Biosketch of the applicant and by a letter from the applicant documenting the importance of the work and the challenges inherent in generating the relevant preliminary data. The applicant must also include a “current support” page that lists current sources of funding, and a letter from the unit head confirming ongoing salary and infrastructure support for the applicant and his/her research program.

Guidelines for application content:

Letter from unit head specifying ongoing salary and infrastructure support for applicant and proposed research (~1 page)

NIH formatted biosketch of applicant(s) (5 pages max)

Specific aims for the proposed R01-type submission. (1 page)

Copy of reviewer comments if a resubmission

Letter outlining: (1) importance of the work and, for established investigators, how it represents a new research direction, (2) gaps in preliminary data that need to be filled in before finalizing the R01-type submission, (3) challenges inherent in generating the relevant preliminary data (~2 pages)

A budget outline and justification for the funds requested towards generating the preliminary data (~1 page)

A list indicating duration and amount of current/pending grant and award support for research in the lab of the investigator(s) (~1 page)

For more information about AFL awards, please visit our website.