What is Transcranial Magnetic Stimulation?

Transcranial magnetic stimulation (TMS) is an FDA-approved, safe and effective treatment for psychiatric conditions including depression, anxiety associated with depression and obsessive-compulsive disorder (OCD). TMS works by using MRI strength magnetic pulses to stimulate specific regions of the brain. It is an outpatient procedure that does not affect cognition so patients can leave the session without assistance and immediately resume their daily activities. TMS is typically recommended when other treatments, such as medications and psychotherapy, have not been helpful. Approximately 50-60% of people with medication-resistant depression will experience a clinically meaningful response with 20-30% reaching full remission, meaning the complete resolution of symptoms. Since TMS

does not involve the use of psychiatric medications, it is also considered in individuals who have difficulties tolerating antidepressants due to side effects.

Eligibility

Major Depressive Disorder (MDD) - An individual between the ages of 18 – 68 may be eligible to receive TMS treatment for MDD if they meet the following criteria:

• Confirmed diagnosis of severe MDD, single or recurrent episode
• Has tried a course of evidence-based psychotherapy, with weekly or greater frequency for at least 6 weeks
• Treatment resistance or inability to tolerate other treatments, demonstrated by at least one of the following:
• At least one failed medication trial in the current depressive episode; or
• History of two medication trials from two different classes; or
• History of treatment with rTMS or electroconvulsive therapy (ECT)
• No significant contraindications (e.g.seizure disorder, metal devices implanted in head or neck)

Obsessive Compulsive Disorder (OCD) - An individual between the ages of 18 – 68 may be eligible to receive TMS treatment for OCD if they meet the following criteria:

• Confirmed diagnosis of OCD
• Has tried a course of evidence-based psychotherapy known to be effective for OCD, with weekly or greater frequency for at least 8 weeks
• Treatment resistance or inability to tolerate other treatments, as demonstrated by at least one of the following:
• At least two failed medication trials administered for a minimum of 8 weeks; or
• History of two medication trials from two different classes; or
• History of treatment with rTMS for OCD; or
• Is currently taking antipsychotics, opioids, benzodiazepines, glutamatergic agents, or other agents which could be considered investigational or risky
• No significant contraindications (e.g.seizure disorder, metal devices implanted in head or neck)

To request an assessment of eligibility for TMS treatment, please complete and submit this form. Note that this content will be reviewed within a timeline that is dependent on our team's ability to schedule an appointment at the time it is received.

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